Latest Coronavirus Medications Approval: Paxlovid (Pill)
Jan. 2022 – The latest treatment for COVID-19 is a pill that’s designed for people who have tested positive for the Coronavirus, and are experiencing severe symptoms. It is especially helpful for people that are not vaccinated or not received booster shot yet. At the moment, it is considered investigational medicine with Emergency Approval by the FDA.
The Center for Disease Control has updated the list of who is more likely to experience potentially life-threatening symptoms. If you have any of the risk factors listed below, we recommend exercising extra caution during this pandemic.
Facts to know about Paxlovid:
- Paxlovid treatment is started as soon as possible after diagnosis of COVID-19 and within 5 days of symptom onset.
- Paxlovid is a treatment for Covid only; not approved for pre- or post-exposure prophylaxis
- Paxlovid supply is currently limited
- Paxlovid is for use in persons 12 years of age and older and older weighing at least 40 kg
- Paxlovid has Many drug-drug interactions.
To reduce your risk of these interactions, talk to your Primary Care doctor, or visit one of our Primary Care Doctors in Southern California. Additionally, you can visit our Covid Page and request a Pre-Screening for expedited access to treatments in case you unfortunately catch the coronavirus in the future.
Who shouldn’t take PAXLOVID?
Do not take PAXLOVID if:
- You are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID.
- You are taking any of the following medicines:
- Pethidine, piroxicam, propoxyphene
- Amiodarone, dronedarone, flecainide, propafenone, quinidine
- Lurasidone, pimozide, clozapine
- Dihydroergotamine, ergotamine, methylergonovine
- Lovastatin, simvastatin
- Sildenafil (Revatio®) for pulmonary arterial hypertension (PAH)
- Triazolam, oral midazolam
- Carbamazepine, phenobarbital, phenytoin
- John’s Wort (hypericum perforatum)
If you are pregnant or breastfeeding, please read the following about taking Paxlovid:
- There is no experience treating pregnant women or breastfeeding mothers with PAXLOVID. For a mother and unborn baby, the benefit of taking PAXLOVID may be greater than the risk from the treatment. If you are pregnant, discuss your options and specific situation with your healthcare provider.
- It is recommended that you use effective barrier contraception or do not have sexual activity while taking PAXLOVID.
- If you are breastfeeding, discuss your options and specific situation with your healthcare provider
PAXLOVID ADVERSE REACTIONS
- Adverse events (incidence ≥1% and ≥5 subject difference) were dysgeusia, diarrhea, hypertension, and myalgia.
- You or your designee must report all SERIOUS ADVERSE EVENTS or MEDICATION ERRORS potentially related to PAXLOVID (1) by submitting FDA Form 3500 online, (2) by downloading this form and then submitting by mail or fax, or contacting the FDA at 1-800-FDA-1088 to request this form. Please also provide a copy of this form to Pfizer Inc. at fax number: 1-866-635-8337.
Possible side effects of PAXLOVID are:
- Liver Problems. Tell your healthcare provider right away if you have any of these signs and symptoms of liver problems: loss of appetite, yellowing of your skin and the whites of eyes (jaundice), dark-colored urine, pale colored stools and itchy skin, stomach area (abdominal) pain.
- Resistance to HIV Medicines. If you have untreated HIV infection, PAXLOVID may lead to some HIV medicines not working as well in the future.
- Other possible side effects include:
- altered sense of taste
- high blood pressure
- muscle aches
- These are not all the possible side effects of PAXLOVID. Not many people have taken PAXLOVID. Serious and unexpected side effects may happen. PAXLOVID is still being studied, so it is possible that all of the risks are not known at this time